Martin seifert genomatix software

Ever wondered how to do first class ngs data analysis without installing software hardware at your site. Martin seifert genomatix pmwc precision medicine world. Martin seifert joined genomatix as vp of business development and consulting in 2004, adding his expertise in chromatin ip, transcriptome analysis, and nuclear receptors to the companys bioinformatics efforts. When a genomatix genomeanalyzer gga is installed inhouse in your institution, it features a bioinformatics workbench which can be accessed locally via ssh for. Genomatix maps future growth at bench and bedside bioit world. Kautzmann, matthew brooks, jacob nellissery, bernward klocke, martin seifert, anand swaroop, the transcriptionsplicing protein nonop54 nrb and three nonointeracting proteins bind to distal enhancer region and augment rhodopsin expression, human molecular genetics, volume 23, issue 8, 15 april 2014, pages 222144. In spring 2004 he joined genomatix adding his expertise in dna. We believe that the combination of microarray databased analyses statistical significance analysis of gene expression with arrayindependent analyses literaturemining and promoter analysis enables some of the problems of traditional array analysis to be overcome. Janne of university of helsinki and dr martin seifert of genomatix software. Martin seifert 4, tatjana borodina 1, aleksey soldatov 1, dmitri parkhomchuk 1, dominic schmidt 1, sean okeeffe 2, stefan haas 2, martin vingron 2, hans lehrach 1, marielaure yaspo 1, 1 department of vertebrate genomics, max planck institute.

By exploiting phylogenetic conservation of cooccurring transcription factor binding sites, a bioinformatics approach has been presented to identify disease causal cisregulatory variants. The scientific excellence and outstanding collaboration in this transcontinental research effort was an a very pleasant. Martin seifert phd is a biologist and managing director of genomatix. Martin seifert, vice president business development and consulting, genomatix software gmbh.

Integrative analysis of deep sequencing data identifies. Examples of ngs data interpretation in personalized medicine martin seifert, ph. A global view of gene activity and alternative splicing by. Munich germany, ann arbor, mi usa march 10, 2010 the c. Martin seifert is chief executive officer at genomatix software gmbh. Genomatix software gmbh is one of the worlds leading suppliers of technologies to analyze and interpret genomic data. For further information please contact eurofins mwg operon dr. Sep 01, 2012 gen genetic engineering and biotechnology news. Magnus rattray, neil lawrence, antti honkela, genomatix ltd. Genomatix is the suppliers of technologies to analyze and interpret genomic data. This is where epigenetic mechanisms become important. Microarray mining is a challenging task because of the superposition of several processes in the data. Michigan 2018 speakers pmwc precision medicine world. Genomatix wins the industriepreis 2012 in the biotech.

After spending some time at brunel university london he accepted the position of head of the microarray facility at the department of cell biology of the technical university of munich. Because of the large amount of data and the need for highend computing power, genomatix deploys its solutions buzzword as inhouse installations hardware software bundle two systems are available. Distributing our software via the cloud infrastructure of basespace will not only. Our hardware, software and service solutions help you analyze microarray and next. The main biological impact is the observation of a new dimension in complexity and variability. A chipseq based approach revealed the key regulatory role of the transcription factor crx and the cisregulatory architecture of photoreceptors. Genomatix software suite and gga new features july 2014 duration. Martin seifert genomatix software gmbh landsberger strasse 6, d80339 munchen genomatix. Active 6 chief executive officer excel connections for martin seifert.

Dysregulation of some of these processes, such as apoptosis, cell proliferation and growth, can lead to cancer. Headquartered in munich germany, genomatix has a global presence by representations in ann arbor, mi usa, paris france, london uk and tokyo japan. Martin seifert, korbinian grote and matthias scherf from genomatix proudly present the industriepreis 2012 trophy and certificate in the biotech category at the hannover. After finishing his phd at the technical university of munich and a year as visiting scientist at brunel university in london, dr. Author summary cellular processes in mammalian cells are tightly regulated to ensure that the cells function properly as a part of an organism. Martin seifert founder and managing director connexome. Integrative analysis of deep sequencing data identifies estrogen. To perform meaningful analysis of their sequencing data. Technologies like genomatix genegrid software provide valuable clinical insights of your individual genomic setup. Transcription factor scan identifies genetic cause for.

Powerful integration of lipid metabolic profiling with gene. Allows identification of transcription factor binding sites tfbs in nucleotide sequences, using a large library of matrix descriptions. Here you can find a list of publications from the members of our team as well as customer and collaborative papers. Mott center for human growth and development, department of obstetrics and gynecology, at the wayne state university school of medicine, in collaboration with the center for molecular medicine and genetics, the karmanos cancer institute and the institute for environmental health sciences, installed a genomatix mining station. Whether you choose our powerful genomatix genome analyzer for onsite analysis or prefer the online genomatix software suite or genegrid variant analysis technology hosted on our secure servers, you will always get results of unprecedented relevance ones that answer precise scientific questions. Genomatix software nextgeneration sequencing for personalized. Matinspector is a tfbs prediction programs that uses the information of core positions, nucleotide distribution matrix and civector to scan sequences of unlimited length for pattern matches. Press release eurofins mwg operon and genomatix announce.

Korbinian grote, nancy bretschneider, bernward klocke, christian zinser, kerstin cartharius, martin seifert genomatix software gmbh, bayerstr. One of the most important regulation mechanisms for cellular processes is via activation of membrane receptors by extracellular stimulus. Janne, george reid and modeling oriented sampsa hautaniemi, magnus rattray, neil lawrence, antti honkela, genomatix ltd. Genomatix is one of the worlds leading suppliers of technologies to analyze and interpret genomic data.

They will support your project every step of the way with their wealth of experience and expertise. A novel genomic alteration of lsamp associates with aggressive prostate cancer in african american men. Promoter analysis based on transcription factor binding sites. A novel genomic alteration of lsamp associates with. Genomatix competitors, revenue and employees owler. Based on the method we could find a significant number of new transcriptional units and splice variants. The software uses a seedbased approach to align reads. Martin seifert, former vice presidentbusiness development. All analyses were performed with default parameters of the software tools. Detecting and visualizing gene fusions jochen supper. Precigen bioinformatics germany gmbh is doing business as genomatix. Physiology, pathology and relatedness of human tissues from. Leveraging crossspecies transcription factor binding site.

Gyorgy petrovics center for prostate disease research, department of surgery, uniformed services university of the health sciences and walter reed national military medical center, bethesda, md 20814, usa. Blueprint to decode the epigenetic signature written in blood. Nov 05, 2007 a recently published research article in the journal of proteome research, authored by researchers from the nestle reserarch center, genomatix software gmbh, rosetta inpharmatics llc, cxr. With our combined hardware software approach, we are able to get the most out of data from next generation sequencing experiments in surprisingly short time. Henk stunnenbergs lab applies genomatix nextgen sequencing.

Martin seifert, vice president business development and. View martin seifert s profile for company associations, background information, and partnerships. Deep sequencing study reveals new insights into human. A biologically intelligent interpretation of genomic. With their unique combination of proprietary algorithms and comprehensive data background, all our solutions do more than enable you to efficiently and effectively analyze and interpret biological data. Martin seifert chief executive officer for genomatix. Simply annotating and aligning dna sequences is not enough to discover their biomedical value, said martin seifert, ph. Search our database of over 100 million company and executive profiles. Genomatix is one of a rapidly growing number of software companies competing in the genome analysis, annotation and interpretation space. When a genomatix genomeanalyzer gga is installed inhouse in your institution, it features a bioinformatics workbench which can be accessed locally via ssh for additional highthroughput analyses. Martin seifert phdis a biologist and managing director of genomatix. Genomatix software gmbh, a systems biology company focussed on high. Martin seifert chief executive for marketing and consulting at genomatix says.

Whether you choose our powerful genomatix genome analyzer for onsite analysis or prefer the online genomatix software suite or genegrid variant analysis technology. In a joint effort of both companies, martin and i organized several workshops on genomics data analysis. Martin seifert, vice president business development and consulting at genomatix says. The scientific excellence and outstanding collaboration in this transcontinental research. His expertise is in chromatin ip, transcriptome analysis and nuclear receptors. As an example, if and how the risk allele rs4684847 contributes to type 2 diabetes has been demonstrated. Genomatix gives a hand in the analysis of wayne states. Synergy is built upon interactive cycles between experimental henk stunnenberg, olli a. About genomatix genomatix software gmbh is a computational biology company headquartered in munich, germany with a seat. A biologically intelligent interpretation of genomic ngs data is critical to this process. Eurofins mwg operon and genomatix announce exclusive.

Genomatix software gmbh is one of the worlds leading suppliers of. Accumulating evidence from our group and others support the contention that biological and genetic alterations differ in prevalence between aa and ca cap chornokur et al. The software modelinspector genomatix was systematically engaged to identify modules in promoter regions. Since 2008 genomatix has strongly focused on next generation sequencing data analysis. Relsci relationships are individuals martin seifert likely has professional access to.

Martin seifert genomatix software gmbh, germany for helpful advice concerning the genomatix software. Genomatix integrates genomewide open chromatin from next. His research focus within genomatix is the development of efficient data analysis instruments for microarray and next generation sequencing data. T werners research works genomatix, munich and other places. Industriepreis 2012 in the biotech category for genomatix at hannover messe. Aug 15, 2008 martin seifert 4, tatjana borodina 1, aleksey soldatov 1, dmitri parkhomchuk 1, dominic schmidt 1, sean okeeffe 2, stefan haas 2, martin vingron 2, hans lehrach 1, marielaure yaspo 1, 1 department of vertebrate genomics, max planck institute for molecular genetics, ihnestrasse 73, 14195 berlin, germany. Press release eurofins mwg operon and genomatix developed.

Over 35,000 researchers worldwide currently apply genomatix tools and databases. Genomatix offers online software and turnkey solutions for the analysis and interpretation in context with copious highquality background data. But its executives believe that the companys forte transcription and gene expression analysis still give it a distinct edge in the marketplace. T werners 15 research works with 2,026 citations and 1,467 reads, including. While you cant change your genome, you can alter the way it is processed. The software can find the potential binding sites of various. Were always happy to tell you more details if any of the papers has sparked your interest and of course were also open to new scientific collaborations. The authors are also grateful to the finnish it centre for science for providing the supercomputing facilities, dr.